In an $80 motel room, a discovery to shed light on the origins of life

https://www.nytimes.com/2026/09/26/science/motel-science-discovery.html

Comments

vixen99Sep 27, 2026, 3:48 PM
Thank you !!
adrian_bSep 27, 2026, 8:42 PM
While the research about Paulinella is very interesting, it has no relationship whatsoever with "the origins of life".

What this research is about is the origin of plants, which are indeed one of the most important forms of life, but the origin of plants is distant by billions of years from the origin of life and it is even distant by billions of years from the origin of phototrophy (frequently, but not really correctly, called "photosynthesis", i.e. the extraction of energy from solar light).

The ancestor of red algae and green algae (the terrestrial plants are descended from green algae) has been created by the hybridization through symbiosis between a unicellular eukaryote (i.e. nucleated cell) and a cyanobacterium, a.k.a. blue-green alga.

As explained in TFA, Paulinella is the second case of such a symbiosis between a nucleated cell and a cyanobacterium, which happened relatively recently, unlike the symbiosis from the origin of plants, which happened about a billion and a half years ago.

Because Paulinella and its internal symbionts have not been modified so profoundly by symbiosis like the red algae or green algae, it can provide information about how the early stages of the hybridization happened, eventually allowing a better understanding of how plants function.

tyreSep 28, 2026, 12:56 AM
> it has no relationship whatsoever with "the origins of life".

followed by

> it can provide information about how the early stages of the hybridization happened

so…

the origins of major parts of life?

thedailymailSep 28, 2026, 5:01 AM
The very next sentence in the comment begins "What this research is about is the origin of plants, which are indeed one of the most important forms of life..."
kulahanSep 27, 2026, 11:06 PM
Isn’t this about the origin of complex life?
adrian_bSep 28, 2026, 6:38 AM
There were several jumps in complexity, this is only one of them.

The first jump in complexity was the appearance of the eukaryotes, a.k.a. nucleated cells, which also happened through hybridization through symbiosis of different kinds of cells.

The event discussed in TFA was the second jump in complexity.

After the ancestor of the red algae and green alga was created by the hybridization of an eukaryote with a cyanobacterium, eventually the cyanobacterium was reduced to a smaller cellular component named chloroplast, which is the site where solar light is captured, and a big part of its DNA has migrated into the nucleus, where it fused with the DNA of the eukaryote host.

Probably after a few hundred million years after the hybridization event, and after the descendants have split into red algae and green algae (the former are adapted to deeper water, which is not reached by the reddish part of the solar light, while the latter are adapted to shallow water with strong light, which enabled them to also spread on the continents, in freshwater), both red algae and green algae evolved multi-cellular forms, which was the next step in increasing complexity.

There is evidence of multi-cellular red algae and green algae from slightly more than a billion years ago. These are the most ancient living beings whose kind can be identified with certainty, because for most unicellular living beings identification is not possible without checking for features that are not preserved in fossils.

The multi-cellular animals, which brought another jump in complexity, appeared only a few hundred million years after the red algae and green algae, in a world where there was a surplus of food from the activity of the abundant algae.

popalchemistSep 27, 2026, 9:15 PM
the origins of plant life is related to the origins of life; even if by abstraction.
NooneAtAll3Sep 27, 2026, 10:34 PM
at best it's related to origins of eucaryotic life, but definitely not whole life in general

we basically uncovered early network sending unencrypted html, and you expect to understand how compiler works - simply different levels of abstraction

popalchemistSep 28, 2026, 1:01 AM
cracking the "origin of life" (I put it in quotes because if you subscribe to the panpsychism premise that consciousness is fundamental then the question of hte origin of life is a bit nonsensical; everything is a permutation of the same primordial life-consciousness) is a bit like cracking AGI; if some new insight gets us closer to the larger question, it is relevant to the larger question even if the larger question is a superset of the sub-question.

It is related in that way.

2b3a51Sep 27, 2026, 5:50 PM
> "He noticed that the scales were overlapping one another in different directions — in one, they overlapped on top of each other in a clockwise pattern, and the other was in reverse. The fresh eyes of a person who hadn’t been staring at Paulinella for hours identified a curious, distinctive trait. Were they looking at two different species?"

I found it reassuring that sketching what you see down the microscope is still part of a scientific practice. Also the 'fresh eyes' could perhaps point the way to a more collegiate organisation of research.

alexpotatoSep 27, 2026, 7:18 PM
> Dr. Van Etten didn’t expect much from the water she had scooped from a random dock next to the highway

There are stories of companies asking their employees to bring back soil and water samples from wherever the employees go on vacation.

The idea is that this is a somewhat random sampling of locations that the company wouldn't have thought of on their own. Plus, it's possible that one of the samples has some novel chemical or biological compound that could lead to a breakthrough discovery.

MisterMunchkinSep 27, 2026, 8:08 PM
If labs want samples like that they should start a scheme, I’d be happy to mail in random stuff.
bromukSep 27, 2026, 8:30 PM
Same! Ready to send random samples from Sheffield
echelonSep 27, 2026, 10:23 PM
We'll likely have robots sampling all over the world's diverse biomes in some short years.
daveguySep 27, 2026, 10:44 PM
I guess that depends on how many robots a company is willing to have stuck in random places.
gregorylSep 28, 2026, 3:22 AM
and/or how many robots they are willing to loose in my shed.
kevmoSep 27, 2026, 7:28 PM
Reminds me of penicillin research, where random cantaloupe from Peoria yielded the best penicillin mold.
staplungSep 27, 2026, 4:55 PM
If you have a decent microscope and want to work on some citizen science that's directly related to the research in this article: https://www.vanettenlab.org/paulinella-consortium
deadbabeSep 27, 2026, 6:24 PM
What is a “decent microscope”?
staplungSep 27, 2026, 7:56 PM
Of course that's a whole discussion but perhaps in the $300 range. Sounds like that's what Dr. Van Etten herself was using when she first found one.

She actually made some specific recommendations on the microscopy sub-reddit but they're a bit pricier ($425+). (scroll to last comment by Jay211TF):

https://www.reddit.com/r/microscopy/comments/1dhagyr/entry_l...

CockbrandSep 27, 2026, 7:46 PM
+1 on this question, without any snark intended. What's a good, not too expensive beginner's microscope that's capable of this kind of citizen research (and other fun stuff)?
chakintoshSep 27, 2026, 7:06 PM
Reading this article with a bittersweet feeling. This is exactly the kind of work I wanted to do for the rest of my life while in Biology class at uni 15 years ago. But I dropped out and ended up in a completely different field (Design). But I still have that fondness of Biology in me all these years later.
pvillanoSep 27, 2026, 8:12 PM
Then buy a microscope and start looking for Paulinella!

https://www.vanettenlab.org/paulinella-consortium

grantsucceededSep 27, 2026, 5:17 PM
this revives my recurring desire to get a good USB microscope. Good, to me, in this context:

a few hundred bucks

able to look at microbes

also able to look at less micro level stuff, like maybe the thing i'm trying to solder or fix

is it wrong to solicit comments/recommendations here?

PhilipRomanSep 27, 2026, 6:16 PM
I'm in the process of building one myself. Take what I'm saying with a massive grain of salt, but I believe you basically need three things - objective, tube lens and a camera module.

If I were you, I would probably buy a normal microscope that supports a microscope camera attachment, instead of specifically looking for USB microscope. There is a lot of misleading marketing around USB microscopes, a lot of them are literally just doing digital zooming in (I have a 30€ "1000x" microscope from Amazon which is nice for soldering and such things, but these fake microscopes appear even at higher price ranges). Treat anything >1000x for light-based microscopes as a red flag.

phyzomeSep 27, 2026, 11:40 PM
My household ended up with a couple of ancient binocular dissecting scopes that a university was throwing out. The magnification isn't amazing, but they're fantastic for just grabbing random shit and looking at it, or yes -- things like soldering.

Ours aren't properly set up for photography, but I did manage to finagle this great shot of a bug curled up inside a hole in the side of a lentil: https://gallery.brainonfire.net/v2/image/18906

The objective lenses are just 1.7x and 3.4x so you can see some cells but not really any details in them. But free is a really good price for that.

ppponeSep 27, 2026, 6:21 PM
Some random ones I've encountered (less for PCB work though):

- https://openflexure.org/

- https://www.eurekamicroscope.com/

staplungSep 27, 2026, 5:46 PM
Perhaps better to ask here: https://www.reddit.com/r/microscopy/. They get that question a lot.
Bayes7Sep 27, 2026, 6:18 PM
>"The first species of Paulinella was discovered on Dec. 24, 1894, in the sediments of a backwater of the Rhine River by the German biologist Robert Lauterborn. He named the genus after his stepmother, Pauline."

How can they say this without providing more background?

____tom____Sep 27, 2026, 6:37 PM
They mention this event has only happened handful of times.

This seems unsupported. More likely is it's happened a large number of times, but has only established a lineage a handful of times.

fyltrSep 27, 2026, 7:51 PM
principle of sparcity. for mutations, we assume it only happened once considering how highly unlikely it is to happen. it is what helps us determine how species are related. if notable differences are detected, like in that case or for example in the case of wings (bird wings vs bat wings), we do an exception.
jll29Sep 27, 2026, 8:13 PM
Once a scientist, always a scientist.

Great reporting - reading this NYT article gives me a little bit of the excitement that I normally only get from reading Quanta Magazine.

tpictSep 27, 2026, 3:35 PM
I wonder what the author thinks steampunk means
dekhnSep 27, 2026, 3:48 PM
Right- that's really just a version of a worm pick. I use similar tools (including a mouth pipette... remember kids, in chemistry: don't pipette by mouth, in biology: oops I think I just inhaled something!) working with tardigrade. If it was steampunk there would be some sort of goggles, leather, gears, and a tincture of laudunum.
aduffySep 27, 2026, 9:50 PM
Maybe I'm getting old but man, motel rooms run $80 now?
whyageSep 27, 2026, 10:57 PM
I'm driving along Route 66 now, and $80 is about the average for a decent motel room.
qginSep 27, 2026, 10:24 PM
If you’re lucky
kulahanSep 27, 2026, 11:07 PM
A cheap one.
GTPSep 27, 2026, 3:31 PM
I have an idea on how life could originate in a motel room :D
nateSep 27, 2026, 6:18 PM
I came here looking for this :) like someone has to be making this joke right. Or another direction of making the connection that there must be some life growing from the filth in a motel room
boie0025Sep 27, 2026, 7:10 PM
Thank you, I came here expecting the same.
BarbingSep 27, 2026, 4:21 PM
Thank you! (Also, haven’t seen this kind of gift link that has the little login requirement, suppose they’re looking to strike a better balance.)
lokeshramchandSep 27, 2026, 4:28 PM
Thank you!
BeijingerSep 27, 2026, 4:29 PM
throwaway81523Sep 28, 2026, 2:20 AM
If they had been willing to chance the $60 room, it would have had even MORE weird microbes!
alpinemanSep 27, 2026, 3:50 PM
All they needed was a blue UV light
kova12Sep 27, 2026, 7:05 PM
You have been blocked from The New York Times because we suspect that you're a robot.

wtf is happening to internet these days...

H1SupremeSep 27, 2026, 7:13 PM
I've seen a big uptick in "prove you're a human" screens recently. Our ISP had issues the other day, and I suspect I was assigned a new IP (I've had previous ones for years). I've been attributing it to that. But, now I'm wondering if it's something else.
alightsoulSep 27, 2026, 11:08 PM
That means your ISP is being used by residential proxies
chaostheorySep 27, 2026, 7:13 PM
I guess their ad platform for LLMs didn’t pan out?
sva_Sep 27, 2026, 5:17 PM
I don't know what I should've expected, but I am a bit disappointed that they in fact did not find these organisms in the motel room.
m3kw9Sep 27, 2026, 3:11 PM
I thought they use built up gunk from years in the bathroom to discover new species, so they choose a cheap motel.
realoSep 27, 2026, 5:35 PM
Quoting the article:

"The team — brought together, in part, by disruptions and despair over the Trump administration’s freezes to federal science funding — then made an exciting discovery."

Apparently this is the new way of life for Scientists under the Trump regime.

Sad.

oofbeySep 27, 2026, 3:45 PM
Why did they work in a motel room? The article kinda implies it had something to do with Trump’s funding cuts, but unless I missed something the connection wasn’t made explicit.
dekhnSep 27, 2026, 3:51 PM
I think it's mainly to be close to the sample collection area while also having a place to do microscopy in semi-privacy. Looking at their equipment, I think they bought everything out of pocket and pay for the hotel on their own.
chrisandchrisSep 27, 2026, 5:26 PM
> The team — brought together, in part, by disruptions and despair over the Trump administration’s freezes to federal science funding — [...]
specprocSep 27, 2026, 6:13 PM
I dunno about the states, but in most parts of the UK, it's considerably cheaper than 80 dollars a day to rent a small workspace.
NetMageSCWSep 27, 2026, 7:06 PM
Near the beach?
sevenartSep 27, 2026, 2:47 PM
non-paywall (perm): https://archive.ph/QpBF1
tombertSep 27, 2026, 8:09 PM
I just stayed in an $80 motel room myself and I also think I might have also discovered a new form of life in the showers.
dfilppiSep 27, 2026, 10:46 PM
[dead]
kstrauserSep 27, 2026, 2:50 PM
[flagged]
_quaSep 27, 2026, 2:51 PM
You think pond water is the worst thing an $80 motel room has seen?
kstrauserSep 27, 2026, 2:56 PM
> Jugs of brackish water lined the walls. Buckets overflowed with hunks of marsh grass.

I don’t know, that goes a little above and beyond IMO. One typically doesn’t do science in a house-type setting, for many of the same reasons you don’t carpet a bathroom.

BrybrySep 27, 2026, 3:12 PM
Probably poetic license. You can look at the pictures and see everything looks very clean.

The jugs are sealed. We can't see any "overflowing" buckets. Looking at some water samples under a microscope is not really that messy.

subscribedSep 27, 2026, 3:08 PM
> for many of the same reasons you don’t carpet a bathroom

For some reason this is a commonplace in the UK.

Yeah....

stephbookSep 27, 2026, 3:24 PM
I had a colleague who walked the tiled floor in front of pissoirs in socks..
subscribedSep 27, 2026, 4:01 PM
Ugh, I just realised my imagination is too good :)
pengaruSep 27, 2026, 3:30 PM
> for many of the same reasons you don’t carpet a bathroom.

someone should inform the orange POTUS of this: https://www.architecturaldigest.com/story/did-donald-trump-j...

mlkihSep 27, 2026, 6:11 PM
[flagged]
ransom1538Sep 27, 2026, 8:36 PM
"Trump administration’s freezes to federal science"

Nytimes can't help itself. love it.

codedokodeSep 27, 2026, 4:40 PM
So $80 is considered a "cheap room"? How is a person supposed to earn $80 a day to pay for it and have something left?

Also, cells can have scales? Amazing.

onlyrealcuzzoSep 27, 2026, 4:46 PM
It takes ~30 minutes to turn around a nightly hotel room, front desk check-in and other labor can easily make that >1h of labor per room per day.

Even in the budget industry, your nightly utility usage comes close to $10, consumables are $3+.

Hotel stays are typically taxed higher than typical sales tax.

Once you add that in, real estate taxes, and any corporate taxes - you're getting close to the $50 price point...

That's before you factor in the cost of maintaining the building, or the financing to buy the building itself (or any profit).

Are we supposed to live in a world where everyone's entitled to be able to stay in hotel rooms for 1 hour of minimum wage labor? Because, until we have far more automation, I don't see how that makes any possible sense.

iso1631Sep 27, 2026, 10:27 PM
There's very little labour cost in your price, not sure where automation would change the cost much.
650REDHAIRSep 27, 2026, 4:44 PM
$80/day is a cheap room in most of the US and Canada.

My standards for hotel rooms on road trips are quite low and I will call the crappy motels to avoid the bloated .com booking rates and it’s not very often I find even 1 star hotels under $80/day after taxes.

dpc050505Sep 27, 2026, 6:39 PM
Per diems in the civil engineering union agreement in my Canadian province are 180$ a day to cover lodging and food when you're working away from home. Most people manage to spend less and save the leftover. That's tax free money unrelated to what you're actually getting paid for the work or transport time.

80$ might seem like a lot of money if you're making 60k a year as a biologist. If you're in a field where profit is the reason you work 80$ is peanuts.

mkirstenSep 27, 2026, 4:44 PM
Have you stayed at hotels? Most people that work don’t stay at hotels and pay the hotel out of pocket.
codedokodeSep 27, 2026, 5:05 PM
I am not from US and with that money I could rent a tiny apartment for 2-3 days. However, I prefer cheaper accomodation. $80 is super expensive if you have no other place to live.
buildsjetsSep 27, 2026, 7:11 PM
I'm currently on a business trip staying a Hampton Inn in a low cost rural area of the USA. The nightly rate is $120. This is not a high end hotel- generally considered 2-star level out of 5. The nearby Comfort Inn is one step lower in quality of accommodation and guests, and gets $75. Anything cheaper than that is a filthy, crime-ridden bucket of blood.
iso1631Sep 27, 2026, 10:31 PM
I'm in Singapore at the moment and it's 200 USD a night for my current hotel, which is near the office - not down town - and not particularly expensive. There are some cheaper ones which aren't on our corporate booking system.

Last week in Beijing it only cost 150 USD at a fairly central Crown Plaza, which I felt was very cheap compared to how much it normally costs in London, and London is a bargain compared to anything I/work pays for in the US (which is mainly in DC and NY)

The flights dwarf the cost of the hotels though, indeed the flights cost more than the cost of me for the two week trip (Work paid a premium to avoid Russian airspace though)

yencabulatorSep 27, 2026, 6:20 PM
In most places, you don't pay the day rate for long stays.
WalterGRSep 27, 2026, 6:17 PM
From my reading of the article, my understanding is that they’re doing science in the hotel room, not living there long-term.
physicaleconSep 27, 2026, 5:07 PM
Motels are not a habitation of last resort by any means. They’re a convenient place to stay while traveling.

I expect the vast majority of motel patrons are additionally paying a rent/mortgage for their main habitation.

thatfrenchguySep 27, 2026, 6:21 PM
Yeah salaries in the US are higher in nominal terms
natedagreat22Sep 27, 2026, 6:49 PM
Where are you from? What would be a normal or comfortable rate for you?
buildsjetsSep 27, 2026, 7:12 PM
You are supposed to be earning more than $80 a day. What do you do for a living that pays $10 an hour?